Tooth mineralization and histology patterns in extinct and extant snaggletooth sharks, Hemipristis (Carcharhiniformes, Hemigaleidae)-Evolutionary significance or ecological adaptation?

Shark jaws exhibit teeth that are arranged into distinct series and files and display great diversities in shapes and structures, which not only is related to their function (grasping, cutting, crushing) during feeding, but also bear a strong phylogenetic signal.So far, most research on the relationship between shark teeth and feeding ecology and s

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HER2-related biomarkers predict clinical outcomes with trastuzumab deruxtecan treatment in patients with HER2-expressing metastatic colorectal cancer: biomarker analyses of DESTINY-CRC01

Abstract DESTINY-CRC01 (NCT03384940) was a multicentre, open-label, phase 2 study that investigated the safety and efficacy of trastuzumab deruxtecan (T-DXd) in patients Rollers with human epidermal growth factor receptor 2 (HER2)-expressing metastatic colorectal cancer (CRC).The present exploratory biomarker analysis aims to investigate relationsh

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Toward a Normalized XML Schema for the GGP Data Archives

Miscellaneous Since 1997, the Global Geodynamics Project (GGP) stations have used a text-based data format.The main drawback of this type of data coding is the lack of data integrity during the data flow processing.As a result, metadata and even data Bag must be checked by human operators.In this paper, we propose a new format for representing the

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